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International Journal of Zoology and Applied Biosciences Review Article
Advances on alternative to animal experimentation: A review
Jaggapu, Sathvika and Vasantha Galanki
Year : 2026 | Volume: 11 | Issue: 4 | Pages: 7-14
Received on: 07/03/2026
Revised on: 14/03/2026
Accepted on: 22/05/2026
Published on: 01/07/2026
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Jaggapu, Sathvika and Vasantha Galanki( 2026).
Advances on alternative to animal experimentation: A review
. International Journal of Zoology and Applied Biosciences, 11( 4), 7-14.
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Abstract
Animals are increasingly being used in experimental to test the safety and effectiveness of medications as medical research and development advances. Millions of animals are utilized annually for experimental experimentation, enduring agony before being ultimately killed. In addition to bio ethical concerns, there are a number of drawbacks to animal experiments, including high expense, the need for trained labor, approval, and time commitment. As a result, scientists have tried to create a variety of substitute techniques that might avoid using animals in study. In addition to providing precise data, these techniques have the potential to save millions of animals’ lives each year. In order to find innovative ways to replace animal testing, research approaches such as computer and robotics as well as molecular biology techniques are used. In this review, several alternative approaches are addressed. Some of these techniques are just as accurate as in-vivo animal models at predicting are just as accurate as in-vivo animal models at predicting how pharmaceuticals would behave. These substitute techniques also have a number of benefits over using animals in experiments. To replace experimental animals, new, precise, and trustworthy techniques must yet be found and developed.
Keywords
Cell culture, Substitute organisms, Refinement, Replacement, Vertebrates.
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© The Author(s) 2025. This article is published by International Journal of Zoology and Applied Biosciences under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
