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International Journal of Zoology and Applied Biosciences Research Article
Prospective observational study on integrating seizure types and etiology for epilepsy, treatment outcomes
B. V. Ramana, M. Bhavyasree, M. Kifayathulla, K. Pradhyumna, S. Khalid
Year : 2026 | Volume: 11 | Issue: 3 | Pages: 95-101
Received on: 24/01/2026
Revised on: 20/02/2026
Accepted on: 01/04/2026
Published on: 01/05/2026
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B. V. Ramana, M. Bhavyasree, M. Kifayathulla, K. Pradhyumna, S. Khalid( 2026).
Prospective observational study on integrating seizure types and etiology for epilepsy, treatment outcomes
. International Journal of Zoology and Applied Biosciences, 11( 3), 95-101.
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Abstract
Epilepsy is a chronic neurological disorder characterized by recurrent seizures, and its management often relies on the accurate identification of seizure type and underlying etiology. Understanding how these factors influence treatment outcomes can improve individualized therapeutic strategies. To evaluate the impact of integrating seizure types and etiological classifications on treatment outcomes in patients with epilepsy through a prospective observational study. This study was conducted in the Department of General Medicine at Government General Hospital, Kurnool. A total of 92 patients (57 males and 35 females; mean age 37.5 years) were enrolled and classified according to International League Against Epilepsy (ILAE) guidelines. Clinical profiles, etiologies, treatment regimens, and seizure control were documented and analyzed. Statistical associations between seizure type, etiology, age, and treatment outcome were evaluated. Generalized tonic-clonic seizures were the most frequent type. Major etiologies included idiopathic epilepsy, alcohol-related causes, and cerebrovascular accidents. Favourable outcomes were seen in 73.9% of patients, moderate recovery in 21.7%, and no recovery in 4.3%. A significant association was found between etiology and treatment outcome (?² = 27.05, p = 0.0076) and between age and recovery (t = 4.15, p = 0.0078), whereas seizure type showed no significant correlation with outcome (p = 0.813). Etiology and patient age are major determinants of therapeutic success in epilepsy, while seizure type alone does not predict outcomes. Incorporating etiological assessment into clinical decision-making can enhance personalized management and improve treatment effectiveness.
Keywords
Epilepsy, Computed tomography, Etiology, Seizure, Patient age.
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© The Author(s) 2025. This article is published by International Journal of Zoology and Applied Biosciences under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
