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International Journal of Zoology and Applied Biosciences Research Article
Phytochemical characterization and pharmacological validation of Butea monosperma leaves used in Gothram traditional medicine
T. Veeraraghavulu, B. Siva Prasad, Venkata Veeranjaneyulu I, V Santhoshi Pravallika, A. Jyotsna and P. Sreenivasa Murthy
Year : 2026 | Volume: 11 | Issue: 3 | Pages: 53-59
Received on: 29/01/2026
Revised on: 21/02/2026
Accepted on: 28/03/2026
Published on: 01/05/2026
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T. Veeraraghavulu, B. Siva Prasad, Venkata Veeranjaneyulu I, V Santhoshi Pravallika, A. Jyotsna and P. Sreenivasa Murthy( 2026).
Phytochemical characterization and pharmacological validation of Butea monosperma leaves used in Gothram traditional medicine
. International Journal of Zoology and Applied Biosciences, 11( 3), 53-59.
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Abstract
Butea monosperma (Lam.) Taub., commonly known as Modhuga, is widely employed in Gothram traditional medicine for the management of inflammatory disorders and wound conditions, yet systematic phytochemical and pharmacological validation of its leaves remains limited. The present study aimed to characterize the phytochemical profile and evaluate the antioxidant and anti-inflammatory potential of Butea monosperma leaves in order to scientifically substantiate its traditional therapeutic claims. A hydroalcoholic leaf extract was subjected to qualitative and quantitative phytochemical screening, HPLC fingerprinting, and in vitro antioxidant assays including DPPH, ABTS, and FRAP methods. The extract demonstrated high total phenolic content (185.6 ± 3.4 mg GAE/g) and total flavonoid content (92.4 ± 2.1 mg QE/g), with significant DPPH radical scavenging activity (IC50 = 42.3 µg/mL) and dose-dependent inhibition of protein denaturation (68.4%). These findings validate the ethnomedicinal use of Butea monosperma leaves in Gothram healing practices, primarily through antioxidant and anti-inflammatory mechanisms mediated by its flavonoid and phenolic constituents.
Keywords
Butea monosperma, Gothram medicine, Anti-inflammatory, Phytochemical analysis, Ethnopharmacology.
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© The Author(s) 2025. This article is published by International Journal of Zoology and Applied Biosciences under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
