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International Journal of Zoology and Applied Biosciences Research Article
Phytochemical profiling, antioxidant and antimicrobial potential of Vitis vinifera l. and Mangifera indica seed extracts
Hareeshthulasi and Rajakumar R
Year : 2026 | Volume: 11 | Issue: 3 | Pages: 284-292
Received on: 17/03/2026
Revised on: 13/04/2026
Accepted on: 22/04/2026
Published on: 31/05/2026
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Hareeshthulasi and Rajakumar R ( 2026).
Phytochemical profiling, antioxidant and antimicrobial potential of Vitis vinifera l. and Mangifera indica seed extracts
. International Journal of Zoology and Applied Biosciences, 11( 3), 284-292.
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Abstract
Plant-derived secondary metabolites are increasingly recognized for their therapeutic relevance and potential applications in nutraceutical and pharmaceutical industries. The present investigation evaluated the phytochemical composition, antioxidant capacity, and antimicrobial activity of seed extracts from Vitis vinifera L. and Mangifera indica. Shade-dried seed powders were extracted using ethanol, acetone and distilled water through cold maceration. Preliminary phytochemical screening indicated the presence of phenolics, flavonoids, tannins, terpenoids, and other secondary metabolites in varying proportions. Ethanolic extracts demonstrated the highest phytochemical abundance. Quantitative analysis revealed significantly greater total phenolic content (TPC) and total flavonoid content (TFC) in V. vinifera ethanolic extract (186.42 ± 4.35 mg GAE/g and 142.63 ± 3.18 mg QE/g, respectively) compared to M. indica. Antioxidant activity assessed by DPPH assay showed concentration-dependent radical scavenging, with V. vinifera exhibiting a lower IC?? (54.28 ± 1.74 µg/mL) than M. indica (72.91 ± 2.06 µg/mL). Broth microdilution assays demonstrated notable antimicrobial activity, particularly against Staphylococcus aureus, with comparatively reduced activity against Gram-negative bacteria. The enhanced biological activity of grape seed extracts is attributed to their higher phenolic and flavonoid concentrations. These findings highlight the potential of fruit seed by-products as sustainable sources of natural antioxidants and antimicrobial agents.
Keywords
Vitis vinifera, Mangifera indica, Phenolics, Flavonoids, Antioxidant activity, Antimicrobial activity, DPPH.
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© The Author(s) 2025. This article is published by International Journal of Zoology and Applied Biosciences under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
