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International Journal of Zoology and Applied Biosciences Research Article
Prevalence, clinical characteristics, and quality of life in phenotypic and endotypic asthma patients at a tertiary care hospital, Kurnool
C. Renuka Thejeshwini, V. Vijay Teja, G. Kirti, M.P. Mercy Amulya, B. Manasa, S. Kusma Kumari
Year : 2026 | Volume: 11 | Issue: 3 | Pages: 180-186
Received on: 14/02/2026
Revised on: 27/02/2026
Accepted on: 20/04/2026
Published on: 01/05/2026
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C. Renuka Thejeshwini, V. Vijay Teja, G. Kirti, M.P. Mercy Amulya, B. Manasa, S. Kusma Kumari( 2026).
Prevalence, clinical characteristics, and quality of life in phenotypic and endotypic asthma patients at a tertiary care hospital, Kurnool
. International Journal of Zoology and Applied Biosciences, 11( 3), 180-186.
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Abstract
Asthma was a chronic inflammatory airway disease characterized by variable airflow obstruction, bronchial hyperresponsiveness, and symptoms such as wheezing, cough, and shortness of breath. It was recognized as a heterogeneous condition with different phenotypic and endotypic variations. The present study was conducted to determine the prevalence, clinical characteristics, and quality of life among patients with different asthma phenotypes and endotypes in a tertiary care hospital. A prospective observational study was carried out among diagnosed asthma patients, and data related to demographics, clinical history, risk factors, and laboratory parameters were collected. Asthma control and quality of life were assessed using standard clinical assessment tools and established guidelines. The study findings indicated that asthma was more common among middle-aged individuals and females. The most frequently observed symptoms included shortness of breath, cough, wheezing, and chest tightness. Environmental exposure, occupational factors, and obesity were identified as major risk factors. Eosinophilic type of asthma was found to be predominant. Improvement in disease control and quality of life was observed following treatment. The study concluded that identification of asthma phenotypes and endotypes was essential for better disease management, and early diagnosis along with individualized treatment significantly improved patient outcomes and quality of life.
Keywords
Asthma Control Test, Asthma, Endotype, Eosinophilia, Phenotype, Quality of Life.
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© The Author(s) 2025. This article is published by International Journal of Zoology and Applied Biosciences under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
